A modular microcavity platform for 3D cell culture.
One platform – three variants, two formats
From routine spheroid culture to oxygen-sensing 3D models: one microcavity architecture, three variants, and two formats – inserts and films.
CaviSphere is a 3D cell culture platform based on microstructured polymer films with defined microcavities. All CaviSphere products share this common architecture and are available as:
3 variants
- MicroSpheres
- PoroSpheres
- SensoSpheres
2 formats
- Ready-to-use cell culture inserts
- Customizable sheets
This makes it easy to start with simple 3D cultures and later extend your setup without changing the underlying platform.
Choosing between MicroSphere, PoroSphere & SensoSphere
All three variants use the same microcavity layouts – they differ in how they interact with your cells and medium.
MicroSphere
For standardised spheroid and organoid culture in defined microcavities.
- Guided formation of uniform 3D structures
- Optimised for microscopy and established 3D assays
- Available as inserts or sheets
PoroSphere
For porous and dynamic 3D cultures where flow and exchange matter
- Porous microcavity walls for co-cultures, permeability and migration assays
- Ideal for microfluidic and Organ-on-Chip setups
- Available as inserts and sheets
SensoSphere
For experiments where oxygen in 3D becomes a key readout.
- Integrated oxygen-sensitive microcavities for real-time monitoring
- Characterisation of oxygen dynamics and gradients in 3D cultures
- Available as inserts or sheets
Inserts or films – which format fits your setup?
Choose inserts if you want a ready-to-use solution in standard plates.
- Minimal integration effort
- Compatible with routine handling, incubation and imaging
- Ideal for academic labs and screening workflows
Choose sheets if you want to integrate CaviSphere into your own devices.
- Flexible integration in Organ-on-Chip and microfluidic systems
- Available with MicroSphere, PoroSphere and SensoSphere architectures
- Ideal for collaborative development and custom setups
Not sure which format is right for you? Use the product finder or contact us for a short discussion.
Start with 3D culture – scale to oxygen-sensing when you are ready
CaviSphere is designed as a continuous path rather than a one-off product decision. Many users:
- begin with MicroSphere or PoroSphere to establish robust 3D models and assays, and
- later add SensoSphere when oxygen becomes an important parameter in their experiments.
Because all variants use the same microcavity concept and are available as inserts and films, you can expand your experimental toolbox without changing your basic workflows.
Ready to explore the CaviSphere platform in your lab?
Whether you work in academic research, drug development, or Organ-on-Chip, we are happy to help you select the right variant and format for your application.