SensoSphere
SensoSpheres are cutting-edge sensor arrays designed to precisely measure oxygen levels in 3D cell cultures. By creating physiologically relevant environments, they enable researchers to study cellular behavior under conditions that closely mimic in vivo systems. With their high-density microcavity structure, SensoSpheres provide accurate and reliable measurements, essential for drug testing, tissue engineering, and organ-on-chip applications. Easy to integrate into existing workflows, SensoSpheres offer a powerful tool to enhance the reproducibility and relevance of experimental results, helping to drive forward research in cell biology and pharmaceutical development.
The oxygen measurements can be easily performed using fluorescence microscopy. In collaboration with PreSens Precision Sensing GmbH, we also offer customized measurement devices and evaluation tools specifically designed for SensoSpheres, ensuring seamless integration into your research workflow. SensoSpheres provide a powerful, flexible solution to improve the accuracy and reproducibility of your experimental results.
For the first time, our system enables the execution of complex assays, such as the Mito-Stress Test, on 3D cell aggregates, allowing for the measurement of changes in oxygen consumption rate (OCR) in the immediate microenvironment of each individual spheroid/organoid. This provides entirely new insights into the effects of drug candidates on cells. Additionally, experiments can be conducted under Physioxia, closely mimicking the oxygen conditions found in human tissues, offering even more accurate and physiologically relevant data for drug development and cellular research.
