MicroSphere –
Standardised 3D microcavity arrays for spheroids and organoids
MicroSphere arrays are the versatile entry point into the CaviSphere® platform. They provide defined microcavities for reproducible spheroid and organoid formation, while remaining easy to implement in everyday lab workflows. With typical cavity diameters between 300 and 800 µm, MicroSpheres are well suited for high‑resolution microscopy and compatible with standard 3D assays.
Whether you are exploring drug responses, studying cellular behaviour in 3D, or establishing new models, MicroSphere offers a robust way to standardise your spheroid and organoid culture – and a straightforward path to more advanced systems such as PoroSphere and SensoSphere.
Key Features:
- Defined microcavities (typically 300–800 µm) for controlled 3D aggregation
- Microscopy-compatible surface for high‑resolution imaging
- Ready for standard viability, toxicity and functional assays
- Available as MicroSphere inserts for 12‑well plates
- Also available as MicroSphere films for integration into custom devices
- Easy upgrade path towards PoroSphere and SensoSphere within the same platform
- Custom configurations available on request
Why use MicroSphere for 3D cell culture?
MicroSphere helps you move from heterogeneous 3D cultures to more standardised models. By guiding cell aggregation into defined microcavities, it supports:
- more uniform spheroid and organoid size distributions
- better comparability between wells and experiments
- efficient use of imaging and assay readouts
Because MicroSphere is part of the CaviSphere platform, protocols and workflows can later be transferred to porous (PoroSphere) or oxygen-sensing (SensoSphere) variants with minimal adjustments.
MicroSphere as inserts and films
MicroSphere is available in two formats to match different ways of working:
MicoSphere Inserts
- Ready-to-use for standard 12‑well plates
- Suitable for routine handling, incubation and imaging
- Ideal for academic labs and screening workflows
MicoSphere Sheets
- Standalone microstructured films for integration into custom devices
- Suitable for microfluidic and Organ-on-Chip setups
- A good choice for collaborative projects and specialised applications
Seamless integration into your workflows
As part of the CaviSphere platform, MicroSphere is designed to integrate into existing equipment and protocols. You can combine it with:
- standard incubators and microscopes
- established staining and assay procedures
- image analysis pipelines for 3D models
If you require specific cavity sizes, geometries or layouts, we can provide customised MicroSphere designs to match your experimental needs.
Not sure if MicroSphere is the right starting point for your 3D model?